Systemic sclerosis (SSc), or scleroderma, is a rare autoimmune condition that results in the thickening and hardening of the skin and internal organs.
Calcinosis (calcium deposits under the skin)
Digestive tract issues (heartburn, dysphagia, acid reflux)
Fatigue
Heart problems (chest pain, abnormal heartbeats)
Joint pain, stiffness, swelling, and loss of mobility
Kidney problems (high blood pressure, kidney failure)
Raynaud's phenomenon (fingers/toes turning white or blue in response to cold or stress)
Skin thickening and tightening
Lung issues (shortness of breath, coughing, lung thickening)
Systemic sclerosis (SSc) is typically classified as limited or diffuse, based on the extent of skin involvement.
Learn more about how people who are experiencing signs and symptoms of systemic sclerosis can be diagnosed.
There are treatments available that may help alleviate symptoms in patients and improve quality of life.
Systemic sclerosis is a rare disease that requires more effective treatment options. To find these new treatments for SSc, further research is necessary.
There are over 170 systemic sclerosis research studies that are actively recruiting participants. Visit ClinicalTrials.gov to find SSc research studies near you.
Find an online community of fellow patients, caregivers, and advocates below as
as well as some other general resources!